The IRE1α Branch of ER Stress Response in Metabolism and Beyond.
Yong Liu, PhD
Professor,
College of Life Sciences
Wuhan University
NCRC Building 10, Room G063-064 or Via Zoom
https://umich.zoom.us/j/94156669540?pwd=VUpqKzVIN2hLTjdZY2JKQktuUG9JQT09
Passcode: CDI
Dr. Liu's research aims to elucidate the molecular mechanisms that link overnutrition, endoplasmic reticulum (ER) stress, and metabolic/ inflammatory disorders. Employing animal models, his team attempts to dissect the physiological actions of the IRE1α arm of the unfolded protein response (UPR) in nutrient-sensing, metabolic control, and immune homeostasis. Their studies will provide new insights into the pathogenic mechanisms underlying obesity, type 2 diabetes, NASH, and other aging-related chronic inflammatory diseases.