Griffin P. Rodgers, MD, MACP, current Director of the National Institute of Diabetes and Digestive and Kidney Diseases recently highlighted the work of the Mouse Metabolic Phenotyping Centers-Live (MMPC-Live) in his NIDDK Director's Winter 2023 Update. Located in only four different academic institutions across the US, the centers provide standardized metabolic and physiological services for live mouse models of diabetes, diabetes complications, obesity and related diseases. The University of Michigan is fortunate enough to be one of the four locations helping investigators standardize and facilitate their work.
We encourage you to visit the MMPC-Live at Michigan website to learn more about the services they provide.
From NIDDK Director's Update Winter 2023
Mouse phenotyping service helps advance metabolic research
Mice used for research can have great variability and be challenging for research replication. But now, NIDDK-funded resources are available to investigators using mouse models to help standardize and facilitate their research. The Mouse Metabolic Phenotyping Centers–Live (MMPC-Live), located at various academic institutions across the United States, provide standardized metabolic and physiologic services for live mouse models of diabetes, diabetes complications, obesity, and related diseases. Researchers can ship live mice to one of the MMPC-Live centers and, on a fee-for-service basis, obtain a range of complex exams used to characterize mouse metabolism, blood composition, energy balance and physical activity, eating and exercise, insulin resistance, organ function, metabolic processes, physiology, histology, and measures of diabetic complications. Many tests are done in living animals and are designed to show subtle-to-complex traits that define models of metabolic disease. For more information about MMPC-Live centers and services, visit the website at www.mmpc.org