Amy E. Rothberg, MD, DABOM is Clinical Professor of Medicine in the Division of Metabolism, Endocrinology and Diabetes and Professor of Nutritional Sciences in the School of Public Health at the University of Michigan. She is the Director of the University of Michigan Weight Management Program, a 2-year intensive behavioral and lifestyle program onto which there is a multifaceted research program in which patients undergo extensive baseline and interval phenotyping to identify the factors that predict successful and cost-effective long-term weight loss. Her primary research is funded by the NIH/NIDDK. Her work encompasses three major research foci: The first is on the impact of the interventions on insulin secretion, insulin action, long-term glycemia, the development of complications and comorbidities, health-related quality-of-life, and cost. The second is on the behavioral and biological determinants of weight loss and weight loss maintenance. The third is scalability of her program through telehealth and the internet and the impact on the processes and outcomes of care.