Biography
The pancreas is a multifunctional organ and is susceptible to a myriad of diseases. We use a combination of in vivo mouse genetics, in vitro human-derived embryonic stem cell differentiations, and ex vivo pancreatic organoid cultures to define the mechanisms by which the pancreas develops, matures, and functions in health and disease with the ultimate goal of improving therapeutic treatments for pancreas disorders, like diabetes and agenesis.
- Ph.D., University of Michigan
Research
Cell signaling, gene regulation, transcription factors, context-specific gene expression, development, cell biology, diabetes, pancreas agenesis, stem cell derived islets, organoids, mouse genetics, disease models
Center, Institute, and Program Affiliations
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